abstract：PURPOSE:To examine the efficacy of corneal collagen cross-linking (CXL) for the treatment of keratoconus (KCN). METHODS:A systemic literature review and meta-analysis of ocular functional and structural parameters of patients with KCN undergoing cross-linking procedures were performed using PubMed and the web of scien...

journal_title：Cornea

authors： Meiri Z,Keren S,Rosenblatt A,Sarig T,Shenhav L,Varssano D

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To evaluate endothelial cell damage after eye bank preparation and passage through 1 of 2 different injectors for Descemet membrane endothelial keratoplasty grafts. METHODS:Eighteen Descemet membrane endothelial keratoplasty grafts were prepared by Lions VisionGift with the standard partial prepeel technique a...

journal_title：Cornea

authors： Schallhorn JM,Holiman JD,Stoeger CG,Chamberlain W

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To present the clinical outcome of 2 cases of severe dry eye associated with Nivolumab, with 1 case progressing to corneal perforation. DESIGN:Case report. CASE 1:: A 58-year-old man with metastatic melanoma was referred for the management of severe bilateral dry eyes after undergoing his sixth cycle of Nivol...

journal_title：Cornea

authors： Nguyen AT,Elia M,Materin MA,Sznol M,Chow J

更新日期：2016-03-01 00:00:00

abstract：PURPOSE:To report 2 cases of ocular chemical burns associated with the use of a swim goggle antifog agent and to review the literature for this and similar antifog products. METHODS:Case reports and systematic review of the medical literature, material safety data, product safety reports, and consumer reviews. RESULT...

journal_title：Cornea

authors： Welling JD,Pike EC,Mauger TF

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:Using CJLAT, a chimeric herpes simplex virus (HSV-1) that produces a high incidence of herpes stromal keratitis (HSK) in latently infected rabbits, and in vivo confocal microscopy (CM), we characterized the cellular events that precede the development of HSK. METHODS:Thirty days after infection, in vivo CM was...

journal_title：Cornea

authors： Jester JV,Morishige N,BenMohamed L,Brown DJ,Osorio N,Hsiang C,Perng GC,Jones C,Wechsler SL

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To investigate the safety of intracameral injection of minimum bactericidal concentration (MBC) of povidone iodine (PI) on the corneal endothelium in a rabbit model as a proposed method of prophylaxis against postoperative endophthalmitis. METHODS:We included 32 New Zealand white rabbits in the study. Twenty-f...

journal_title：Cornea

authors： ElKitkat RS,Ebeid WM,Habib EK,Shoukry Y

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:To describe a novel technique for removal of Descemet membrane (DM) tags or remnants in hazy corneas during Descemet stripping automated endothelial keratoplasty. METHODS:The DM tags or remnants may be difficult to visualize in the presence of hazy corneas. To identify and remove the residual DM remnants and t...

journal_title：Cornea

authors： Sharma N,Sharma VK,Arora T,Singh KR,Agarwal T,Vajpayee RB

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:Pterygium excision with conjunctival limbal autograft (CLAG) has been used successfully for prevention of pterygium recurrence. However, long-term follow-up data in the literature are lacking regarding CLAG. METHODS:Retrospective chart review and standard statistical analysis were performed. The records of 289...

journal_title：Cornea

authors： Masters JS,Harris DJ Jr

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:This study explored a new method for removing thermosensitive acrylic punctal plugs from lacrimal puncta. METHODS:A total of 14 dry eye patients (14 eyes), who required the removal of thermosensitive acrylic punctal plugs from the lacrimal puncta because of serious complications, were recruited. Among the 14 p...

journal_title：Cornea

authors： Zhang M,Zhang X

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To analyze tear meniscus dimensions with Fourier domain-optical coherence tomography (FD-OCT) in patients with type 2 diabetes mellitus. METHODS:Patients with type 2 diabetes without diabetic retinopathy (DR) (n = 54), with nonproliferative DR (n = 45), with proliferative DR (PDR) (n = 25), and controls (n = 4...

journal_title：Cornea

authors： Baek J,Doh SH,Chung SK

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To assess the clinical outcomes after sequential surgical implantation of intracorneal ring segments and transepithelial corneal collagen cross-linking (TE-CXL) in keratoconic eyes. METHODS:In this consecutive randomized study, 40 eyes of 29 patients with progressive mild to moderate keratoconus were included ...

journal_title：Cornea

authors： Elsaftawy HS,Ahmed MH,Saif MY,Mousa R

更新日期：2015-11-01 00:00:00

abstract：:An understanding of corneal optics is important to optimize the visual outcome after eye surgery. Recent advances in the surgical techniques of lamellar keratoplasty have changed the strategies used for corneal transplantation. Lamellar keratoplasty has the advantage of having a lower rate of graft rejection, superior...

journal_title：Cornea

authors： Yamaguchi T,Satake Y,Dogru M,Ohnuma K,Negishi K,Shimazaki J

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:To evaluate the stromal interface quality after femtosecond laser full lamellar cuts in gamma-irradiated corneas (VisionGraft sterile cornea) and to determine the limits of the cut depth using the VisionGraft as donor corneas for laser-assisted lamellar anterior keratoplasty. METHODS:Fourteen VisionGraft corne...

journal_title：Cornea

authors： Zhang C,Liu L,Tang M,Li Y,Chamberlain W,Huang D

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:To report 2 cases of corneal perforation associated with a persistent epithelial defect (PED), which were treated with eye drops containing the fibronectin-derived peptide PHSRN (Pro-His-Ser-Arg-Asn). METHODS:A 67-year-old man and a 58-year-old man presented with corneal perforation associated with a PED cause...

journal_title：Cornea

authors： Morita Y,Morishige N,Yamada N,Ohta M,Sonoda KH,Nishida T

更新日期：2015-11-01 00:00:00

abstract：PURPOSE:To compare the visual results, higher-order aberrations, and corneal biomechanical properties of femtosecond small incision lenticule extraction (SMILE) at depths of 100 and 160 μm. METHODS:A prospective comparative interventional clinical trial of a series of patients who underwent SMILE. In the right eye, a ...

journal_title：Cornea

authors： El-Massry AA,Goweida MB,Shama Ael-S,Elkhawaga MH,Abdalla MF

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To describe the efficacy of combined excimer laser photoablation and amniotic overlay membrane in the relief of symptomatic discomfort in a 17-year-old patient who had gelatinous drop-like corneal dystrophy. METHODS:The best-corrected visual acuity (BCVA) was measured with Snellen letters. Slit-lamp examinatio...

journal_title：Cornea

authors： Alex AF,Eter N,Uhlig CE

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:Little research has been done on robotic ocular microsurgery. This study aims to demonstrate the feasibility of pterygium surgery using a robotic surgical system. METHODS:Robot-assisted pterygium surgery was performed on a 73-year-old patient with nasal and temporal pterygia using the DaVinci Si HD robotic Sur...

journal_title：Cornea

authors： Bourcier T,Chammas J,Becmeur PH,Danan J,Sauer A,Gaucher D,Liverneaux P,Mutter D

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy and safety of autologous serum (AS) eye drops combined with punctal plugs (PPs) in patients with Sjögren syndrome (SS)-related dry eye. METHODS:A retrospective clinical study was performed in patients with dry eye caused by SS. We evaluated the Schirmer test value, tear breakup time (t...

journal_title：Cornea

authors： Liu Y,Hirayama M,Cui X,Connell S,Kawakita T,Tsubota K

更新日期：2015-10-01 00:00:00

abstract：PURPOSE:To analyze whether plasma rich in growth factors (PRGF) eye drops preserve their biological characteristics and activity after storage for 3 and 6 months at -20°C, at 4°C, and at room temperature for 72 hours, compared with fresh samples (t0). METHODS:Blood from 6 healthy donors was harvested and centrifuged t...

journal_title：Cornea

authors： Anitua E,de la Fuente M,Riestra A,Merayo-Lloves J,Muruzábal F,Orive G

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To investigate the regulation of matrix metalloproteinase (MMP)-3 and MMP-13 expression over time and in the presence of cyclosporine A (CsA) in primary cultured human pterygium fibroblasts. We also examined the effects of CsA on cultured human pterygium fibroblasts. METHODS:Primary cultured human pterygium fi...

journal_title：Cornea

authors： Kim YH,Jung JC,Jung SY,Kim YI,Lee KW,Park YJ

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:To report a patient with refractory keratitis after a Boston type I keratoprosthesis treated with corneal collagen cross-linking (CXL). METHODS:Case report. RESULTS:A 29-year-old man with a history of chemical burn in the left eye underwent keratoprosthesis implantation. He developed infectious keratitis 4 mo...

journal_title：Cornea

authors： Zarei-Ghanavati S,Irandoost F

更新日期：2015-09-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the visual function information obtained from multiple reading tests in a dry eye population. METHODS:In this case-control, single-center clinical research center-based study, 15 subjects with dry eye (mean age 65 years) and 10 normal subjects (mean age 40 years) were incl...

journal_title：Cornea

authors： Ousler GW 3rd,Rodriguez JD,Smith LM,Lane KJ,Heckley C,Angjeli E,Abelson MB

更新日期：2015-08-01 00:00:00

abstract：PURPOSE:To investigate the changes of meibomian gland (MG) and tear film stability in subjects with eyelid tattoos. METHODS:Forty female subjects were recruited. Ten subjects had eyelid tattoos and 30 subjects did not (control group). Tear film break-up time (TBUT) measurement and fluorescein staining were performed t...

journal_title：Cornea

authors： Lee YB,Kim JJ,Hyon JY,Wee WR,Shin YJ

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:To report the outcomes of corneal fine needle diathermy (FND) with adjuvant intrastromal and subconjunctival bevacizumab injection for corneal neovascularization (CN) in children. METHODS:Medical records of all children who had undergone FND with adjuvant bevacizumab injection were reviewed retrospectively. Tr...

journal_title：Cornea

authors： Elbaz U,Mireskandari K,Shen C,Ali A

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:To report intraoperative and 1-year postoperative results of the pachy-bubble technique for deep anterior lamellar keratoplasty (DALK). METHODS:This prospective interventional case series included 110 eyes of 107 patients with anterior corneal pathology who underwent DALK, including 78 with keratoconus. Outcom...

journal_title：Cornea

authors： Ghanem RC,Bogoni A,Ghanem VC

更新日期：2015-06-01 00:00:00

abstract：PURPOSE:To report a solitary epibulbar neurofibroma in 2 elderly patients without systemic neurofibromatosis. METHODS:Case reports and literature review. RESULTS:A 67-year-old man presented with a 2-month history of left epibulbar mass. On slit-lamp examination, an 8- × 8-mm amelanotic, translucent, gelatinous, circu...

journal_title：Cornea

authors： Tanaka TS,Elner VM,Demirci H

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine whether long-term wear of a fluid-filled scleral lens alters basal tear production, corneal sensation, corneal nerve density, and corneal nerve morphology in 2 disease categories. METHODS:Patients recruited from the Prosthetic Replacement of the Ocular Surface Ecosystem (...

journal_title：Cornea

authors： Wang Y,Kornberg DL,St Clair RM,Lee M,Muhic I,Ciralsky JB,Alzaga Fernandez A,Sood P,Sippel KC,Rosenblatt MI

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:To describe the clinical features, disease course, management, and visual outcome of stromal microsporidial keratitis involving the corneal graft in an immunocompetent patient. METHODS:Case report. RESULTS:We report the case of a 21-year-old immunocompetent woman, who underwent penetrating keratoplasty for ad...

journal_title：Cornea

authors： Pradhan S,Mascarenhas J,Srinivasan M

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to determine the effect of nicergoline in patients with neurotrophic keratopathy. METHODS:This is a prospective, noncomparative interventional study. The study included 27 eyes of 24 patients with neurotrophic keratopathy who were unresponsive to conventional therapy. Patients were tr...

journal_title：Cornea

authors： Lee YC,Kim SY

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To study the factors affecting the time to onset of ocular graft-versus-host disease (GVHD) in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). METHODS:A retrospective chart review of 200 patients with ocular GVHD was performed to evaluate the association between various do...

journal_title：Cornea

authors： Shikari H,Amparo F,Saboo U,Dana R

更新日期：2015-03-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the effectiveness of punctal occlusion using hypromellose 2% in patients with dry eye. METHODS:In this prospective, randomized single-blinded clinical trial, we evaluated 76 eyes of 38 patients (36 women and 2 men) with dry eye secondary to rheumatic diseases. In each pati...

journal_title：Cornea

authors： Capita L,Chalita MR,dos Santos-Neto LL

更新日期：2015-02-01 00:00:00

abstract：PURPOSE:The aim of this study was to compare topographic and biomechanical properties of corneas in patients with acromegaly with those of healthy individuals. METHODS:Thirty-five patients with acromegaly (study group) and 35 healthy individuals (control group) were enrolled in this prospective study. Topographic meas...

journal_title：Cornea

authors： Altinkaynak H,Duru N,Ersoy R,Kalkan Akcay E,Ugurlu N,Cagil N,Cakir B

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Laser-assisted epilation of eyebrow hair has become a common practice, but a number of ocular complications can occur. We report the cases of 2 patients who had unilateral anterior uveitis after having undergone laser removal of eyebrow hair. METHODS:This report describes 2 patients who experienced eye pain, p...

journal_title：Cornea

authors： Gunes A,Yasar C,Tok L,Tok O

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To report the case of a patient who initially presented with primary acquired melanosis (PAM) without atypia of the conjunctiva and later developed lentigo maligna of the eyelids and PAM with atypia of the conjunctiva. We illustrate the utility of combination topical therapy with adjunctive cryotherapy to treat...

journal_title：Cornea

authors： Bratton EM,Knutsen-Larson S,Durairaj VD,Gregory DG,Mellette JR

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the corneal thickness asymmetry indices in a large pool of patients with keratoconus derived using anterior segment optical coherence tomography (AS-OCT) in comparison with established Scheimpflug imaging-derived keratoconus classification indices. METHODS:Six specific ...

journal_title：Cornea

authors： Kanellopoulos AJ,Asimellis G

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:To report that spontaneous postkeratoplasty wound dehiscence or gaps caused by suture removal may occur years after penetrating and deep lamellar keratoplasty. METHODS:We retrospectively reviewed the medical records of 667 keratoplasty patients (890 eyes). This study included 8 eyes of 8 patients (3 men and 5 ...

journal_title：Cornea

authors： Fujii S,Matsumoto Y,Fukui M,Fujitake J,Kawakita T,Shimmura S,Tsubota K

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate the reliability of tear film osmolarity as a diagnostic tool for detecting dry eye disease (DED) in patients with rheumatoid arthritis (RA). The second aim was to determine whether there is a relationship between tear film osmolarity, a commonly used RA score, and diagnosti...

journal_title：Cornea

authors： Schargus M,Wolf F,Tony HP,Meyer-Ter-Vehn T,Geerling G

更新日期：2014-12-01 00:00:00

abstract：PURPOSE:The aim of this study was to evaluate preparation outcomes of tissue prepared for Descemet membrane endothelial keratoplasty (DMEK) from diabetic and nondiabetic donors. METHODS:In this nonrandomized, consecutive case series, DMEK grafts were prepared from diabetic and nondiabetic donors by experienced technic...

journal_title：Cornea

authors： Greiner MA,Rixen JJ,Wagoner MD,Schmidt GA,Stoeger CG,Straiko MD,Zimmerman MB,Kitzmann AS,Goins KM

更新日期：2014-11-01 00:00:00

abstract：:Corneal photorefractive surgery is currently performed by ablation of corneal stroma under the stromal flap. A stromal flap is created using a femtosecond (FS) laser or mechanical microkeratome, although the FS laser procedure is considered safer and more accurate. This review assesses and compares the use of FS laser...

journal_title：Cornea

authors： Sumioka T,Miyamoto T,Takatsuki R,Okada Y,Yamanaka O,Saika S

更新日期：2014-11-01 00:00:00

abstract：:Decompensation of the corneal endothelium causes severe visual impairments that lead to blindness. Although corneal transplantation is a well-known effective therapy for corneal endothelial dysfunction, many patients are not afforded that therapeutic opportunity owing to the worldwide shortage of donor corneas. Thus, ...

journal_title：Cornea

authors： Okumura N,Kinoshita S,Koizumi N

更新日期：2014-11-01 00:00:00